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Grant of the Government of the Russian Federation for the state support of scientific researches, which are conducted under the guidance of leading scientists in Russian educational institutions of higher professional education (agreement No. 11.G34.31.0065 dated October 19, 2011)

Regeneration of airways and lung

The official website of the project "Investigating the molecular mechanisms and underlying pathways of regenerative medicine approaches the tissue-engineering and cell therapy of airways and lungs"

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Hydrogel derived from decellularized ventricular extracellular matrix increases cardiomyocyte survival and preserves post-myocardial infarction

The study reported in the Journal  American College of Cardiology evaluated the use of an injectable hydrogel derived from ventricular extracellular matrix (ECM) for treating myocardial infarction (MI) and its ability to be delivered percutaneously. There was  developed a myocardial-specific hydrogel, derived from decellularized ventricular ECM  of  female rats underwent ischemia reperfusion followed by injection of the hydrogel or saline 2 weeks later. The hydrogel was delivered by the NOGA-guided MyoStar catheter (California). There was  demonstrated that injection of the material in the rat MI model increases endogenous cardiomyocytes in the infarct area and maintains cardiac function without inducing arrhythmias. The  results warrant further study of this material in a large animal model of MI and suggest this may be a promising new therapy for treating MI.

http://content.onlinejacc.org/cgi/content/citation/57/14_Suppl_S/E2017?elq=92a7cb4ee9df4c99974e5cce5c89a9f6

2012 Kuban State Medical University. The official website of the project "Investigating the molecular mechanisms and underlying pathways of regenerative medicine approaches the tissue-engineering and cell therapy of airways and lungs"